MicroRNAs (miRNAs) are a type of small non-coding RNAs that play an essential role in numerous biological processes by regulating the Pop Up Tunnel post-transcriptional expression of target genes.Recent studies have demonstrated that miR-192-5p, a member of the miR-192 family, partakes in several human diseases, especially various cancers, includin
Abstract Background CRISPRi screening has become a Laptop Accessories powerful approach for functional genomic research.However, the off-target effects resulting from the mismatch tolerance between sgRNAs and their intended targets is a primary concern in CRISPRi applications.Results We introduce Guide Library Designer (GLiDe), a web-based tool spe
Abstract Unlike in the bulk, at the nanoscale shape dictates properties.The imperative to understand and predict nanocrystal shape led to the development, over several decades, of a large number of mathematical models and, later, their software implementations.In this review, the various mathematical approaches used to model crystal shapes are firs
Disaster forensic investigation analyses the unfolding of a disaster and attempts to identify its multiple causes of damage which can lead to (i) improved disaster prevention and management from lessons learnt, and (ii) more effective mitigation measures in the aftermath of a disaster.The way in which damage data are collected after a flood event a